The following are guidlines for individuals to consider genetic counseling and testing.
If you have a family history of BREAST/OVARIAN CANCER.....
If you have a family history of COLON/UTERINE Cancer.....
BREAST/OVARIAN CANCER
Consider genetic counseling if you have a personal and/or family history of:
- Breast cancer diagnosed before age 45.
- Multiple cases of breast cancer on the same side of the family.
- Ovarian cancer in a family with breast cancer.
- Male breast cancer.
- Multiple cases of pancreatic cancer on the same side of the family.
- The combination of breast, ovarian, and/or pancreatic cancer on the same side of the family or in a single individual.
- Jewish ancestry in combination with any of the above.
- Jewish ancestry and even one case of breast or ovarian cancer (even in the absence of additional family history).
- Medullary breast cancer and triple negative breast cancer are over-represented in women with hereditary breast and ovarian cancer.
COLON CANCER
Consider genetic counseling if you have a personal and/or family history of:
- Colon cancer diagnosed before age 50.
- Multiple cases of colon cancer on the same side of the family.
- The combination of colon, uterine, ovarian, urinary tract, and/or other gastrointestinal cancers on the same side of the family.
- A single individual with colon and uterine cancer, more than one separate colon cancer diagnosis, or colon and ovarian cancer.
- Even one sebaceous carcinoma.
- A colon cancer in which screening tests (called microsatellite instability (MSI) and/or immunohistochemistry (IHC)) have indicated an increased risk for hereditary colon cancer.
- Multiple colon polyps (adenomatous, hamartomatous, or juvenile).
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