Christina Applegate

Christina Applegate was recently diagnosed with breast cancer at age 36 and learned that she carries a BRCA1 mutation. Her family history includes her mother who was diagnosed with early-onset bilateral breast cancer. Ms. Applegate pursued a bilateral mastectomy.

As many of you know, BRCA mutation carriers are at increased risk for a second primary breast cancer, either in the affected or unaffected breast. This lifetime risk ranges from 40-64% and is due to the fact that the BRCA mutation is present in every breast cell. For women who carry a BRCA mutation, bilateral mastectomy significantly reduces the risk of a second primary breast cancer.

For more information please click on the light blue link above "Christina Applegate." To view her video interview with Good Morning America please search "Christina Applegate" on the GMA website.